📊 VC Pulse

Venture Capital Intelligence Report

December 28, 2025 • Synthesizing insights from top-tier VCs

🌍 Macro Outlook

Overall Sentiment

CAUTIOUS

Key Themes

AI Infrastructure ScalingDefense & National Security TechPost-ZIRP Reality Check

Market View

VCs are seeing a bifurcated market: AI infrastructure and defense tech commanding premium valuations while consumer and traditional SaaS face compression. Flight to quality continues as LPs demand cleaner metrics.

Funding Environment

Series A/B rounds taking 20-30% longer to close. Seed still active but Series C+ requiring clear path to profitability. Corporate VCs stepping in more for strategic rounds.

Valuation Trends

AI infrastructure maintaining 15-25x revenue multiples while traditional software compress to 6-10x. Early-stage pre-revenue AI companies still getting premium treatment.

🔥 Hot Sectors

AI Infrastructure & Compute 🔥🔥🔥 HOT

The picks-and-shovels play for AI gold rush. Hardware, specialized chips, and infrastructure software seeing massive demand as enterprises scale AI workloads.

📈 Stage: Series A 🏢 Examples: CoreWeave, Modal, Cerebras
Key Opportunities:
  • Custom silicon for AI workloads
  • Multi-cloud orchestration
  • GPU virtualization
Risks:
  • NVIDIA dependency
  • Cloud provider competition
a16zSequoiaBenchmarkLightspeed
Defense & Dual-Use Technology 🔥🔥🔥 HOT

Geopolitical tensions driving massive government spending. VCs betting on companies that can serve both commercial and defense markets with advanced technology.

📈 Stage: Growth 🏢 Examples: Anduril, Palantir, Shield AI
Key Opportunities:
  • Autonomous systems
  • Cyber defense
  • Space technology
Risks:
  • Government contract dependency
  • Long sales cycles
Andreessen HorowitzFounders FundLux Capital
Vertical AI Agents 🔥🔥 WARM

Moving beyond general LLMs to specialized AI agents for specific workflows. Higher defensibility through domain expertise and proprietary data.

📈 Stage: Series A 🏢 Examples: Harvey, Glean, Hebbia
Key Opportunities:
  • Legal AI workflows
  • Healthcare diagnostics
  • Financial analysis
Risks:
  • Model commoditization
  • Data moat sustainability
GreylockIndex VenturesGeneral Catalyst
Climate Infrastructure 🔥🔥 WARM

IRA funding catalyzing massive infrastructure build-out. Focus shifting from R&D to deployment and scale manufacturing of proven technologies.

📈 Stage: Growth 🏢 Examples: Form Energy, Commonwealth Fusion, Sila Nanotechnologies
Key Opportunities:
  • Grid modernization
  • Energy storage
  • Clean manufacturing
Risks:
  • Policy dependency
  • Long payback periods
Breakthrough EnergyKleiner PerkinsBessemer
Enterprise AI Security 🔥🔥 WARM

As AI adoption accelerates, enterprises need new security frameworks. Massive opportunity in AI model security, data governance, and compliance.

📈 Stage: Series A 🏢 Examples: Lakera, Arthur AI, Robust Intelligence
Key Opportunities:
  • AI model security
  • Data privacy compliance
  • Prompt injection defense
Risks:
  • Evolving regulatory landscape
  • Integration complexity
AccelLightspeedIndex

🔦 VC Spotlight

Andreessen Horowitz
Katherine Boyle
2024-12-15
AI + American Dynamism convergence driving next wave of defense innovation

The best defense tech companies will be AI-first from day one, not legacy contractors adding AI as feature

"We're entering an era where software eats defense, and AI eats software"
Defense TechAI Infrastructure
Contrarian View: Betting heavily on AI-powered autonomous weapons systems despite ESG concerns
Sequoia Capital
Pat Grady
2024-12-10
Compound startups: AI + traditional industries creating entirely new markets

The biggest opportunities are where AI enables completely new business models, not just efficiency gains

"Don't build an AI company. Build a company that happens to use AI to do something impossible before"
Vertical AIHealthcare AI
Contrarian View: Most horizontal AI tools will be commoditized; only vertical solutions with proprietary data will win
Benchmark
Eric Vishria
2024-12-05
Infrastructure software in the age of AI requires fundamentally different architecture

Traditional databases and infrastructure weren't designed for AI workloads - complete reimagining needed

"We're seeing the biggest infrastructure platform shift since cloud computing"
AI InfrastructureDeveloper Tools
Contrarian View: Vector databases are just the beginning - entire data stack needs rebuilding for AI

🌱 Emerging Themes

🌱 AI-Native Government Mainstream adoption by 2027-2028

Government agencies building AI-first systems rather than retrofitting legacy infrastructure

Why Now:

New administration pushing AI adoption, DARPA increasing AI research funding, government efficiency mandates

Market Potential:

$200B+ government IT spending could shift to AI-native solutions

Early signals from: Lux Capital, Founders Fund, 8VC

Companies to watch: Scale AI, Primer, Rebellion Defense

🌱 Compound AI Systems Enterprise adoption accelerating through 2025

Multiple specialized AI models working together rather than single general-purpose LLMs

Why Now:

Cost optimization driving specialized models, better performance on domain-specific tasks

Market Potential:

Could reduce AI inference costs by 10-100x while improving accuracy

Early signals from: Greylock, Kleiner Perkins, NEA

Companies to watch: Together AI, Mistral, Anthropic

🌱 Neuromorphic Computing Commercial viability by 2026-2027

Brain-inspired computing architectures for ultra-low power AI inference

Why Now:

Edge AI demands, sustainability concerns, breakthrough in chip design

Market Potential:

Could enable AI in every IoT device - trillion device opportunity

Early signals from: Intel Capital, Samsung Ventures, Founders Fund

Companies to watch: BrainChip, SynSense, Innatera

❄️ Cooling Sectors

❄️ Consumer Social/Creator Economy

Previous: Red hot during 2020-2021 with massive rounds → Now: Significantly cooled, limited new funding

User acquisition costs skyrocketing, iOS privacy changes, limited monetization options, platform dependency risks

What Changed: Post-iOS 14.5 reality hit hard, TikTok dominance makes new social extremely difficult

VCs Cautious: Benchmark, General Catalyst, Accel

❄️ NFT/Web3 Gaming

Previous: Billions invested in 2021-2022 → Now: Minimal new investment, focus on utility

User adoption failed to materialize, tokenomics proved unsustainable, regulatory uncertainty

What Changed: Market realized speculation ≠ sustainable gaming economy

VCs Cautious: Most traditional VCs backing away

❄️ Traditional SaaS

Previous: Dominant category for decade → Now: Compressed valuations, higher bars

Market saturation, AI threatening to automate many workflows, customer consolidation pressure

What Changed: AI making traditional software workflows obsolete faster than expected

VCs Cautious: Most growth-stage VCs

👨‍💻 Founder Insights

AI Defensibility

Data network effects and proprietary inference optimization are the only sustainable moats in AI

💡 Focus on creating unique datasets through user interactions rather than just model fine-tuning

— Sequoia Capital

Enterprise AI Sales

Chief AI Officers are emerging as new buyer persona - different from traditional IT buyers

💡 Tailor sales process to CAOs who care more about business outcomes than technical specifications

— Bessemer Venture Partners

Fundraising Strategy

Show clear path to positive unit economics by Series B or expect significantly longer fundraising cycles

💡 Model out profitability scenarios early and optimize for capital efficiency from day one

— General Catalyst

AI Regulation Prep

EU AI Act compliance becoming table stakes for enterprise AI companies globally

💡 Build compliance frameworks into product architecture now rather than retrofitting later

— Accel

💰 Deal Activity

Deal volume down 35% YoY but average deal size up 20%. Clear bifurcation between AI/defense winners and everything else struggling

🚀 Mega Rounds

Anthropic $4B

Series C • Lead: Amazon • Others: Google, Spark Capital

Shows continued mega-investment in foundation model companies despite commoditization concerns

Foundation Models
Anduril Industries $1.5B

Series E • Lead: Founders Fund • Others: a16z, General Catalyst

Largest defense tech round signaling institutional acceptance of defense investing

Defense Technology

🚪 Notable Exits

UiPath $10.2B

Take-Private • Key investors: Accel, CapitalG, Kleiner Perkins

Traditional RPA being valued as legacy tech despite AI integration efforts

🎯 Contrarian Takes

Founders Fund

Their View

Open source AI will lose to proprietary models in enterprise

VS
Consensus

Most believe open source will commoditize AI

Reasoning: Enterprise customers will pay premium for guaranteed performance and support

Their Bet: Backing proprietary model companies like Anthropic heavily

Benchmark

Their View

Consumer AI products will emerge as breakout category in 2025

VS
Consensus

Consumer AI has failed to find product-market fit

Reasoning: Interface breakthroughs and cost reductions creating new opportunities

Their Bet: Seed investments in stealth consumer AI companies

🔮 Predictions

First $100B AI infrastructure company emerges by 2026

HIGH

Andreessen Horowitz • Timeframe: 2026

Implications: Would create massive new category of infrastructure investing and validate AI infrastructure as permanent category

50% of new enterprise software will be AI-native by end of 2025

MEDIUM

Sequoia Capital • Timeframe: 2025

Implications: Traditional SaaS companies without AI strategy will become uninvestable

Government becomes largest buyer of AI services, surpassing enterprise by 2027

SPECULATIVE

Lux Capital • Timeframe: 2027

Implications: Would shift entire AI industry focus toward compliance and security over pure innovation

📌 Key Takeaways

1 AI infrastructure remains the safest bet with sustained demand and pricing power
2 Defense tech has broken into mainstream VC with institutional acceptance
3 Traditional software categories face existential threat from AI automation
4 Vertical AI applications showing more defensibility than horizontal tools
5 Fundraising environment favoring capital-efficient companies with clear unit economics
6 Regulatory compliance becoming competitive advantage rather than cost center
7 Open source vs proprietary AI debate far from settled, creating investment opportunities

👁️ What to Watch

👁️ GPU utilization rates at major cloud providers

Leading indicator of AI infrastructure demand sustainability

Bullish

Sustained 80%+ utilization indicates continued infrastructure investment

Bearish

Dropping utilization suggests AI investment bubble deflating

👁️ Enterprise AI adoption metrics from major consultancies

Real adoption vs hype indicator for B2B AI companies

Bullish

Accelerating enterprise deployment validates vertical AI thesis

Bearish

Slow adoption suggests need for more infrastructure before applications

👁️ Government AI procurement announcements

Could create massive new market for AI companies

Bullish

Major federal AI contracts signal new mega-customer category

Bearish

Procurement delays indicate regulatory/security obstacles